Medium-dependent activity of immune serum on Brucella-infected macrophages.
نویسندگان
چکیده
Medium constituents affect the inhibitory action of anti-Brucella melitensis serum during in vitro infection of oil-induced peritoneal macrophages of the guinea pig with B. melitensis.
منابع مشابه
Osmotically sensitive Brucella in infected normal and immune macrophages.
When Brucella suis is grown in tissue cultures of normal guinea pig macrophages, the Brucella multiplies significantly without the induction of osmotically sensitive forms. In immune macrophages in the presence of normal guinea pig serum, there is a reduction in the number of intracellular Brucella and no multiplication is seen over a 72-hr period. After 6 hr of exposure to immune macrophages, ...
متن کاملSerum-mediated immune cellular responses to Brucella melitensis. IV. Infection of macrophages under anaerobic conditions.
Immune mechanisms active against Brucella were studied under conditions of oxygen deficiency. B. melitensis grew in rabbit serum-Tyrode medium flooded with N(2) and CO(2) gas mixtures. Immune sera from rabbits injected with B. melitensis strain Rev I possessed growth-inhibitory activity that operated in anaerobic environments against Rev I and virulent strain 6015. When mixed with macrophages, ...
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Background & Objective: One of the most common diseases between zoonosis - especially in developing countries – is brucellosis. Identification of Brucella cell antigen combinations in terms of the amount and type of immune response in infected hosts, are important in vaccine design. 31kDa Brucella cell surface protein (BCSP31) is shared among all Brucellae. We aimed to define specific immune r...
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متن کاملComparative protection of mice against virulent and attenuated strains of Brucella abortus by passive transfer of immune T cells or serum.
Passively transferred immune serum provided significantly greater protection to BALB/c mice against attenuated Brucella abortus 19 than against virulent strain 2308, whether serum donors had been infected with strain 19 or 2308. In contrast, immune T cells conferred better protection upon recipients challenged with the homologous strain of B. abortus. It is hypothesized that strain 2308, but no...
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عنوان ژورنال:
- Infection and immunity
دوره 3 2 شماره
صفحات -
تاریخ انتشار 1971